Kliničke karakteristike endobronhijalne tuberkuloze

  • Natalija Samardžić Clinic for Lung Disease, Clinical Center of Serbia, Belgrade, Serbia
  • Dragana Jovanović Clinic for Lung Disease, Clinical Center of Serbia, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia
  • Ljiljana Marković-Denić Faculty of Medicine, University of Belgrade, Belgrade, Serbia; Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
  • Marina Roksandić - Milenković Clinic for Lung Disease, Clinical Center of Serbia, Belgrade, Serbia
  • Spasoje Popević Clinic for Lung Disease, Clinical Center of Serbia, Belgrade, Serbia
  • Vesna Škodrić-Trifunović Clinic for Lung Disease, Clinical Center of Serbia, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia
DOI: https://doi.org/10.2298/1852
Ključne reči: tuberculosis, pulmonary||, ||tuberkuloza pluća, diagnosis||, ||dijagnoza, signs and symptoms||, ||znaci i simptomi, radiography||, ||radiografija, bronhoscopy||, ||bronhoskopija, histological techniques||, ||histološke tehnike,

Sažetak


Uvod/Cilj. Endobronhijalna tuberkuloza (EBTB) je tuberkuloza traheobronhijalnog stabla, mikrobiološki i/ili patohistološki potvrđena. Cilj rada bio je da se odrede kliničke karakteristike i dijagnostički aspekt endobronhijalne tuberkuloze. Metode. Ova retrospektivna studija sprovedena je u Klinici za plućne bolesti Kliničkog centra Srbije u Beogradu u periodu od januara 1997. do kraja decembra 2007. god. Analizirani su svi bolesnici sa EBTB koja je potvrđena bronhoskopski i biopsijom u navedenom periodu. Prikupljeni su anamnestički podaci bolesnika, podaci o fizikalnom pregledu i radiografiji pluća, laboratorijske analize sputuma, uz bronhoskopsku i patohistološku potvrdu. Rezultati. U studiji je bilo 57,6% osoba muškog pola. Najčešći simptomi bolesti bili su kašalj (71,2%), znojenje (54,2%), povišena telesna temperatura (49,2%), gubitak telesne mase (40,7%) i hemoptizije (13,6%). Kod većine bolesnika dijagnoza je postavljena unutar 30 dana od početka simptoma. U sputumu je kod 31,4% bolesnika potvrđen Mycobacterium tuberculosis, a kultura je bila pozitivna kod 55,9% bolesnika. Na radiografskom nalazu najčešće su bili zahvaćeni gornji režnjevi pluća (kod 63,5% bolesnika). Kaverne je imalo 60,4% bolesnika. Bronhoskopski nalaz je kod najvećeg broja pokazivao nespecifični bronhitis (39,9%) i edemohiperemični podtip EBTB (36,4%). Zaključak. U našoj zemlji EBTB je značajno češća kod muškaraca i osoba u pedesetim godinama života. Bronhoskopski nalaz koreliše sa kliničkim i laboratorijskim nalazom i omogućava lakše postavljanje dijagnoze i pravovremenu terapiju.

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Objavljeno
2015/04/21
Broj časopisa
Vol. 71 Br. 2 (2014)
Rubrika
Originalni članak