Ekstramedularni plazmocitom baze jezika: retka prezentacija plazmocitoma glave i vrata

  • Jelena Sreten Bila Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia
  • Boško Andjelić Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia
  • Jelena Bodrožić Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia
  • Ljubomir Jaković Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia
  • Maja Peruničić Jovanović Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia
  • Ana Vidović Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia,Faculty of Medicine, University of Belgrade, Belgrade, Serbia
  • Milena Todorović Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia,Faculty of Medicine, University of Belgrade, Belgrade, Serbia
  • Mihaljević Biljana Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia,Faculty of Medicine, University of Belgrade, Belgrade, Serbia
DOI: https://doi.org/10.2298/1438
Ključne reči: plasmacytoma||, ||plazmocitom, diagnosis||, ||dijagnoza, tongue||, ||jezik, radiotherapy||, ||radioterapija, treatment outcome||, ||lečenje, ishod,

Sažetak


 

Uvod. Posebni entiteti kao što su solitarni plazmocitom kostiju ili ekstramedularni plazmocitom (EMP) mogu se naći kod manje od 5% bolesnika sa plazmaćelijskim oboljenjima. Ekstramodularni plazmocitom baze jezika je veoma retka lokalizacija plazmocitoma glave i vrata. Prikaz bolesnika. U radu je prikazana bolesnica, stara 78 godina, sa EMP baze jezika, čije postojanje je ustanovljeno magnetnom rezonancom (MR) glave i vrata. Imunohistohemijskim profilom bioptata tumorskog tkiva (CD38, IgG, kappa pozitivnost) potvrđena je dijagnoza EMP. Dopunskim ispitivanjima ustanovljeno je odsustvo drugih manifestacija bolesti. Bolesnica je lečena lokalnom zračnom terapijom sa 40 Gy u 20 seansi, čime je postignuta kompletna remisija bolesti. Zaključak. Ekstramodularni plazmocitom baze jezika je veoma redak vid ispoljavanja plazmaćelijskih oboljenja. Odgovarajućom zračnom terapijom postižu se dugotrajne remisije bolesti uz postojanje potencijalne mogućnosti izlečenja.

 

 


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Objavljeno
2017/01/20
Broj časopisa
Vol. 70 Br. 10 (2013)
Rubrika
Prikaz bolesnika