Finger and foot tapping sensor system for objective motor assessment

  • Milica Djurić-Jovičić University of Belgrade, Innovation Center School of Electrical Engineering
  • Nenad Jovičić School of Electrical Engineering
  • Sasa M Radovanovic Institute for Medical Research, Belgrade
  • Milica Ječmenica Lukić Institute for Medical Research
  • Minja Belić School of Electrical Engineering
  • Mirjana Popović University of Belgrade, School of Electrical Engineering, Institute for Medical Research
  • Vladimir Kostić University of Belgrade, Faculty of Medicine, Belgrade, Serbia; Clinical Center of Serbia, Clinic for Neurology
Keywords: parkinson disease;, muscle tonus;, neurophysiology;, toe phalanges;, hand;, fingers;, equpment and supplies;, serbia

Abstract


Background/Aim. Finger tapping test is commonly used in neurological examinations as a test of motor performance. The new system comprising inertial and force sensors and custom proprietary software was developed for quantitative estimation and assessment of finger and foot tapping tests. The aim of this system was to provide diagnosis support and objective assessment of motor function. Methods. Miniature inertial sensors were placed on fingertips and used for measuring finger movements. A force sensor was placed on the fingertip of one finger, in order to measure the force during tapping. For foot tapping assessment, an inertial sensor was mounted on the subject’s foot, which was placed above a force platform. By using this system, various parameters such as a number of taps, tapping duration, rhythm, open and close speed, the applied force and tapping angle, can be extracted for detailed analysis of a patient’s motor performance. The system was tested on 13 patients with Parkinson’s disease and 14 healthy controls. Results. The system allowed easy measurement of listed parameters, and additional graphical representation showed quantitative differences in these parameters between neurological patient and healthy subjects. Conclusion. The novel system for finger and foot tapping test is compact, simple to use and efficiently collects patient data. Parameters measured in patients can be compared to those measured in healthy subjects, or among groups of patients, or used to monitor progress of the disease, or therapy effects. Created data and scores could be used together with the scores from clinical tests, providing the possibility for better insight into the diagnosis.

References

Giovannoni G, van Schalkwyk J, Fritz VU, Lees AJ. Bradykinesia akinesia in co-ordination test (BRAIN TEST): An objective computerized assessment of upper limb motor function. J Neurol Neurosurg Psychiatry 1999; 67(5): 624−9.

Raethjen J, Austermann K, Witt K, Zeuner KE, Papengut F, Deuschl G. Provocation of Parkinsonian tremor. Mov Disord 2008; 23(7): 1019−23.

Gunzler SA, Pavel M, Koudelka C, Carlson NE, Nutt JG. Foot-tapping rate as an objective outcome measure for Parkinson disease clinical trials. Clin Neuropharmacol 2009; 32(2): 97−102.

Mendonca DA, Jog MS. Tasks of attention augment rigidity in mild Parkinson disease. Can J Neurol Sci 2008; 35(4): 501−5.

Holmes G. The symptoms of acute cerebellar injuries due to gunshot injuries. Brain 1917; 40: 461−535.

Notermans NC, van Dijk GW, van der Graaf Y, van Gijn J, Wokke JH. Measuring ataxia: Quantification based on the standard neurological examination. J Neurol Neurosurg Psychiatry 1994; 57(1): 22−6.

Heller A, Wade DT, Wood VA, Sunderland A, Hewer RL, Ward E. Arm function after stroke: Measurement and recovery over the first three months. J Neurol Neurosurg Psychiatry 1987; 50(6): 714−9.

Ott BR, Ellias SA, Lannon MC. Quantitative assessment of movement in Alzheimer's disease. J Geriatr Psychiatry Neurol 1995; 8(1): 71−5.

Fahn S, Elton RL. Committee mot UD. Unified Parkinsons Disease Rating Scale. In: Fahn S, Marsden CD, Goldstein M, Calne DB, editors. Recent developments in Parkinson's disease II.. New York: MacMillan; 1987. p. 153−63.

Agostino R, Berardelli A, Curra A, Accornero N, Manfredi M. Clinical impairment of sequential finger movements in Parkinson's disease. Mov Disord 1998; 13(3): 418−21.

Agostino R, Curra A, Giovannelli M, Modugno N, Manfredi M, Be-rardelli A. Impairment of individual finger movements in Par-kinson's disease. Mov Disord 2003; 18(5): 560−5.

Goetz CG, Stebbins GT. Assuring interrater reliability for the UPDRS motor section: Utilityof UPDRS teaching tape. Mov Disord 2004; 19(12): 1453−6.

Hatayama T, Hatayama M, Kikuchi N. A mobile device for mea-suring sensorimotor timing in synchronized tapping. Percept Mot Skills 2004; 98(3 Pt 2): 1327−32.

Ling H, Massey LA, Lees AJ, Brown P, Day BL. Hypokinesia without decrement distinguishes progressive supranuclear pal-sy from Parkinson's disease. Brain 2012; 135(Pt 4): 1141−53.

Jobbágya Á, Harcos P, Karolya R, Fazekas G. Analysis of finger-tapping movement. J Neurosci Methods 2005; 141(1): 29−39.

Lainscsek C, Rowat P, Schettino L, Lee D, Song D, Letellier C, Poizner H. Finger tapping movements of Parkinson's disease patients automatically rated using nonlinear delay differential equations. Chaos 2012; 22(1): 013119.

Okuno R, Yokoe M, Akazawa K, Abe K, Sakoda S. Finger taps movement acceleration measurement system for quantitative diagnosis of Parkinson's disease. Conf Proc IEEE Eng Med Biol Soc 2006; Suppl: 6623-6.

Muir SR, Jones RD, Andreae JH, Donaldson IM. Measurement and Analysis of Single and Multiple Finger Tapping in Normal and Parkinsonian Subjects. Parkinsonism Related Dis 1995; 1(2): 89−96.

Yokoe M, Okuno R, Hamasaki T, Kurachic Y, Akazawa K, Sakoda S. Opening velocity, a novel parameter, for finger tapping test in patients with Parkinson's disease. Parkinsonism Related Dis 2009; 15(6): 440−4.

Stamatakis J, Cremers J, Macq B, Garraux G. Finger Tapping feature extraction in Parkinson's disease using low-cost accelerometers. Proceedings of the 10th IEEE International Conference on Information Technology and Applications in Biomedicine; 2010 November 3−5; New York: Conf Proc IEEE Eng Med Biol Soc 2010. p. 1−4.

Shima K, Tsuji T, Kan E, Kandori A, Yokoe M, Sakoda S. Mea-surement and evaluation of finger tapping movements using magnetic sensors. Conf Proc IEEE Eng Med Biol Soc 2008; 2008: 5628−31.

Djurić-Jovičić M. Inertial sensors signal processing methods for gait analysis of patients with impaired gait pattern [disserta-tion]. Belgrade: School of Electrical Engineering, University of Belgrade; 2012. (Serbian)

Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: A clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992; 55(3): 181−4.

Folstein MF, Folstein SE, Mchugh PR. "Mini-mental State". A practical method for grading the cognitive state of patients for the clinician. J Psychiatric Res 1975; 12(3): 189−98.

Dubois B, Slachevsky A, Litvan I, Pillon B. The FAB: A frontal assessment battery at bedside. Neurol 2000; 55(11): 1621−6.

Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23(1): 56−62.

Hoehn MM, Yahr MD. Parkinsonism: Onset, progression and mortality. Neurology 2001; 57(10 Suppl 3): S11−26.

Tomlinson CL, Stowe R, Patel S, Rick C, Gray R, Clarke CE. Systematic review of levodopa dose equivalency reporting in Parkinson's disease. Mov Disord 2010; 25(15): 2649−53.

Arias P, Robles-García V, Espinosa N, Corral Y, Cudeiro J. Validity of the finger tapping test in Parkinson's disease, elderly and young healthy subjects: Is there a role for central fatigue?. Clin Neurophysiol 2012; 123(10): 2034−41.

Djurić-Jovičić M, Petrović I, Ječmenica-Lukić M, Radovanović S, Dragasević-Miskovic N, Belić M, et al. Finger tapping analysis in patients with Parkinson's disease and atypical parkinsonism. J Clin Neurosci 2016; 30: 49−55.

Published
2020/10/22
Section
Original Paper