SCLEROCHOROIDAL CALCIFICATION MIMICKING CHOROIDAL OSTEOMA: A CASE REPORT

SCLEROCHOROIDAL CALCIFICATION

  • Dolika Vasović University Clinical Centre of Serbia
  • Dejan M. Rašić Eye Hospital University Clinical Centre of Serbia
  • Mirjana Mitrović Mitrovic Eye Clinic, Belgrade, Serbia
Keywords: sclerochoroidal calcification, choroidal osteoma, fluorescein angiography, calcified intraocular lesions

Abstract


Introduction: Sclerochoroidal calcifications are uncommon, benign ocular findings characterized by the deposition of calcium and phosphate within the sclera and adjacent choroid. These lesions are most frequently discovered incidentally during routine ophthalmologic evaluation, particularly in elderly individuals, and may resemble more serious intraocular pathologies.

Case report: We present the case of a 62-year-old male patient referred for evaluation of a subretinal lesion in the peripheral retina of the left eye, initially detected during a routine ophthalmologic examination. The patient was asymptomatic, with no visual complaints. Fundus examination revealed a yellowish, placoid lesion with indistinct borders located suprapapillary, between the superior vascular arcades. B-scan ultrasonography demonstrated high internal reflectivity with posterior acoustic shadowing. Fluorescein angiography revealed a hypofluorescent lesion without leakage or staining. The lesion remained stable over several years, and systemic workup showed no evidence of metabolic abnormalities. Based on clinical and imaging findings (B-scan ultrasonography and fluorescein angiography), the diagnosis of sclerochoroidal calcification was established.

Conclusion: Sclerochoroidal calcifications may clinically and ultrasonographically mimic more serious intraocular lesions. B-scan ultrasonography and fluorescein angiography, play a key role in distinguishing these benign findings from other conditions. In asymptomatic patients without signs of progression, annual follow-up is recommended, with no need for therapeutic intervention.

References

Gündüz AK, Tetik D. Diagnosis and management strategies in sclerochoroidal calcification: a systematic review. Clin Ophthalmol. 2023 Sep 11;17:2665-86. doi: 10.2147/OPTH.S399058.

Shields CL, Hasanreisoglu M, Saktanasate J, Shields PW, Seibel I, Shields JA. Sclerochoroidal calcification: clinical features, outcomes, and relationship with hypercalcemia and parathyroid adenoma in 179 eyes. Retina. 2015 Mar;35(3):547-54. doi: 10.1097/IAE.0000000000000450.

Honavar SG, Shields CL, Demirci H, Shields JA. Sclerochoroidal calcification: clinical manifestations and systemic associations. Arch Ophthalmol. 2001 Jun;119(6):833-40. doi: 10.1001/archopht.119.6.833.

Mani X, Johnson R. A case of sclerochoroidal calcification masquerading as a retained intraocular foreign body. Radiol Case Rep. 2023 Mar 25;18(5):2034-8. doi: 10.1016/j.radcr.2023.02.049.

Sood S, Friedman S. Sclerochoroidal calcification with optic nerve calcification in a patient with primary hyperparathyroidism and severe vision loss. Retin Cases Brief Rep. 2024 Jul 1;18(4):499-502. doi: 10.1097/ICB.0000000000001418.

Lopez JM, Rabinovich M, Colantuono D, Souied EH. Multimodal and retro-mode imaging in sclerochoroidal calcification: a case report. Arch Soc Esp Oftalmol (Engl Ed). 2024 May;99(5):213-7. doi: 10.1016/j.oftale.2024.02.002.

Thomson AC, Brown GT, Dolores-Rodriguez A, Hunter AA. A Case of extensive bilateral idiopathic sclerochoroidal calcification and review of literature. Int Med Case Rep J. 2021 Oct 28;14:749-55. doi: 10.2147/IMCRJ.S336237.

Brahma VL, Shah SP, Chaudhry NA, Prenner JL. Bilateral idiopathic sclerochoroidal calcifications. Open Ophthalmol J. 2017 Apr 27;11:76-9. doi: 10.2174/1874364101711010076.

Published
2025/10/06
Section
Case reviews